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its pedicle was smaller than an ordinary lead pencil, and length, on either side of the needle. The occlusion here was quite translucent.

OVARIOTOMY.

DR. PEASLEE exhibited an ovarian tumor which he had removed from a patient the Saturday before. He first detected the growth in April, it being then about two inches and a half in diameter, and supposed it a monocyst. He only saw the patient again a few weeks ago, and although the size of the tumor had not increased as high up as the umbilicus, he was struck with the inroads which it had made upon the patient's health. He proposed that she should be tapped at once, which was done three weeks before he removed the tumor. He obtained from the sac about three quarts of a fluid that resembled very much in physical qualities the pea soup. This caused a perfect collapse of what he supposed to be a monocyst, and which was all that was left, except a body to the side of it that felt like an inverted saucer. To his surprise the sac, instead of taking several months to refill, was enlarged to its full dimensions in the course of three weeks, the consequence of which was an earlier operation than was anticipated. The incision was only three inches in length, but the tumor, which proved to be of considerable size, and polycystic withal, was removed by tapping one cyst at a time and drawing it outside of the wound until all were emptied. There were only a few slight adhesions in the median line. The pedicle, which was very delicate, and about the width of the hand, was secured by a strong double ligature passed through its middle and tied both ways, after which the pedicle was returned. He presented the specimen to illustrate two points: the first regarded the development of tumors upon what appeared to be a monocyst; and the second had reference to the small size of a tumor which could give rise to such an amount of mischief. The Society then adjourned.

STATED MEETING, JAN. 22, 1868.

DR. WM. B. BIBBINS, PRESIDENT, in the Chair.

ACUPRESSURE AND ITS EFFECTS.

DR. HUTCHISON presented some specimens illustrating the effects of acupressure on the arteries of sheep, dogs, and men, and remarked upon them as follows::

The specimen which I have here, marked number three, is the left carotid of a sheep ten days after acupressure in continuity, the needles having been removed fifty hours after they were applied. The specimen shows that the coats of the artery have been cut through (except at the posterior part), and that more pressure was consequently applied than was necessary. It shows two very decided plugs, one on the distal and one on the cardiac side of the needle. The orifices of each part of the vessel were closed up with lymph, and firmly plugged together. Just at the opening of the vessel there was an occlusion, the coats firmly joining together by lymph. The blow-pipe was introduced into each extremity of this vessel while under water, and no air could be made to pass through, showing them to be entirely occluded.

The second specimen (number four) is the right carotid of a sheep four days after acupressure. The needles in this case were removed in seventy-four hours. Two needles were applied here by the fourth method of Sir James Simpson, and the artery divided between. I intended these to have been removed forty-eight hours after the operation, but they were forgotten by the gentleman with whom I left the animal in charge. The specimen shows large clots, an inch and a half in

of both extremities was so complete that no air could be passed through when the specimens were placed under water. When the needles were removed no hemorrhage took place.

The specimen marked number five, was the popliteal artery removed along with amputation seven days and nineteen hours after acupressure. The needle was. removed forty-eight hours after acupressure was employed. The patient had an extensive lacerated wound of the lower and outer part of the right leg, for which he was admitted to the Brooklyn City Hospital. There was some hæmorrhage from the branch of the anterior tibial artery, which was arrested by the acupressure needle, which in its turn was removed thirteen hours after.

Subsequently erysipelas supervened, attended with extensive sloughing of the soft parts. The patient ran down rapidly in consequence of this, and it was necessary to amputate his leg at the knee-joint, to save his life. In this case, in consequence of inflammation, the small vessels were so much enlarged that it was necessary to apply ten needles, by the various methods. This artery was closed by the fifth method. It was done very promptly, and very efficiently, and on examining the specimens the results are seen. The patient died subsequently from exhaustion, seven days and nineteen hours after the operation. After the needle was applied to the popliteal, pulsation was plainly seen in the vibrations of the glass at the end of the needle; this condition continued until the instrument was removed. I was satisfied that the artery must be closed sufficiently to take away the needle, and to prove that I was right, I would state that no hemorrhage followed its withdrawal. The specimen shows quite a firm red clot, which is not adherent to the vessel except at its extremity. The mouth was firmly closed by lymph. I also introduced a blow pipe into this vessel while it was under water, and was unable to get any air through it.

Specimen number six is the posterior tibial artery, removed from a man who came into the Brooklyn City Hospital on the 2d of January, with a compound comminuted fracture of both bones of the leg. He had, as proved after the amputation, though not recognized before, a rupture of the anterior tibial, from which he bled considerably. I ascertained that the House Surgeon attempted to ligate this vessel, but did not succeed.

Amputation was performed the following day, the limb being removed just below the tubercle of the tibia. Three vessels, the anterior and posterior tibial and muscular branch, were closed by the acupressure needles. The third, fourth, and fifth methods, were used in this case, respectively. The fourth method was employed on this vessel. The operation was performed by Dr. Cochrane, and with his permission the needles were applied. Two hours subsequently I was requested to see the patient, who was suffering from secondary hæmorrhage; and I was told that pressure over the femoral had failed to arrest it. I deemed it safest to open the wound, and for this purpose removed the metallic sutures. I sought for the source of the hæmorrhage, and found those vessels to which the needles had been applied perfectly dry. The bleeding came from two muscular branches, which had not bled at the time of the operation, although the wound was kept open for some time. This bleeding came on after an effort at vomiting, and after he reacted. These were arrested by acupressure, and some oozing from the end of the tibia was checked by the application of the persulphate of iron. This patient vomited continuously after the stump had

been opened, and gradually sank afterwards and died of
exhaustion. The specimen shows a clot very well
marked, not adherent except at the extremity. The
anterior tibial was not preserved in making the dissec-
tion.
Specimen number 7 is the right carotid of a dog. An
acupressure needle was applied to the vessel in its
continuity, and was removed in twenty-five hours. The
animal was killed by the ether which was used to bring
on the anesthesia for the second operation. The vessel
shows on its cardiac side a plug about an inch and a half
in length; on the opposite side the plug is about an inch
and a third in length. It appears that in this case there
was rather more pressure used than was necessary, for
in examining it carefully I find that the coats have
given away and have been absorbed by pressure in
front. The vessel is, however, firmly plugged, as the
air could not be forced through it while under water.
I think that the reason why the artery has not yielded
to pressure as in the human subject, is the small amount
of elastic tissue which it contains.

maturely and from sloughing, which not infrequently extends beyond the seat of the plug. By means of acupressure we simply compress the coats of the artery together; no violence is used, the coats are not disturbed at all, and there is on that account less liability to secondary hæmorrhage. Mr. Perry, of Aberdeen, who has used this method more than any one else, is strongly in its favor, and although, in company with Mr. Keith and Mr. Fides, of the hospital of that place, he has applied it to eight hundred arteries, only two instances of secondary hæmorrhage have occurred.

The great value of acupressure, however, and its adoption or rejection in the majority of cases, will depend upon our ability to obtain union by the first intention in large wounds. Dr. Perry states that in fifty-one capital operations there were twenty-one in which union by the first intention occurred. These comprised amputations of the leg, thigh, arm, and the removal of mammary glands and large tumors. By union by first intention he means union without the formation of a single drop of pus; if a single drop of pus is observed he rejects the case.

In answer to questions by various of the members, he explained the different methods of acupressure as advised by Simpson, of Edinburgh.

MALIGNANT DISEASE OF LARYNX, ETC.

DR. BRADLEY next exhibited a specimen of disease of the larynx, which was removed at the post-mortem examination of an Englishman, fifty-four years of age. The following history was given: The man had always been healthy up to a year ago last February. There was no hereditary taint in his family, and his father lived to the age of ninety-three, and his mother to eighty-seven. He first noticed a difficulty in swallowsuddenly from the table and complain of something choking him, become for a time strangulated, and then sit down and finish his meal. This continued until the first of June, from which time he was unable to swallow any solids. He first came under observation at the Dispensary about the first of October, and Dr. Bradley saw the patient at intervals from that time until his death. Bromide of potassium was administered, and it is thought with some relief. He did not complain of any pain in the larynx, but located all his uneasy sensations in that locality, and, after all, he got on well enough until he attempted to swallow solid food. His case was examined by the laryngoscope, and as near as the speaker could remember, there was found some thickening behind the arytenoid cartilages.

The next specimen was removed this afternoon. It is the left carotid of a sheep vivisected forty-seven hours after acupressure. The vessel shows a plug on both sides of the needle, and it is firmly occluded, as I ascertained by attempting to pass air through it under water. These specimens, in company with those presented at a previous meeting, comprise my experience with acupressure. It has been employed in twenty-eight arteries in man and five or six in the lower animals. Among other operations in which it was employed were, two amputations of the leg, one at knee-joint and one of foot, and one of wound in the radial artery which latter, by the way, illustrated the value of acupressure in a striking manner. The patient had suffered from an extensive lacerated wound in the lower parting at the time referred to. He would get up very of the forearm and hand, and, several days after, sloughing took place followed by hemorrhage from the radial artery. The bleeding was very profuse, so much so that the patient lost a pint and a half of blood in a very few minutes. The artery was exposed in the midst of sloughing tissue. The tourniquet had been applied and also the persulphate of iron; these were, however, removed and acupressure needles slipped under the artery above and below, with the effect of arresting the hæmorrhage in an instant. The needles were removed at the end of twenty-two hours. The following day the patient had hemorrhage from the superficialis volæ from the same cause. The blood oozed out very freely, and a considerable quantity was lost before the house-surgeon could arrive to arrest it. This Dr. Elbrig did by the method of acupressure with a very satisfactory result. The patient finally died of starvation. On making This latter needle was removed at the end of twenty- the post-mortem examination, as soon as the omo-hyoid seven hours. These two cases illustrate very strongly muscle was cut through where it comes up alongside of the value of acupressure in certain cases. I believe the larynx, pus exuded. The larynx was then opened that if a ligature had been applied premature slough-into in front, and an ulceration of its posterior wall was ing might have resulted, with its attendant hæmor- found, which extended from above the cricoid cartilage rhage. In either case, in order to prevent this occur- throughout its whole extent and along the posterior rence, it would have been necessary to have applied a wall of the trachea as far down as its bifurcation. This ligature in sound tissue above and below the wound, to ulceration and deficiency of tissue was about four inches have made a very long, tedious, and unsatisfactory dis in extent; the whole of the trachea was opened for section, with the result, as before stated, of having about four inches, and the oesophagus, which lay in imsecondary hæmorrhage afterwards. mediate contact, had also disappeared by ulceration. The rest of the larynx and the vocal cords looked quite healthy.

The value of acupressure is, of course, not fully known. Yet it has been demonstrated that we can by these means certainly arrest hæmorrhage. I am dis- The specimen had been examined microscopically by posed to think that secondary hæmorrhage is less apt Dr. Rogers, who declared it to be a rare example of to occur after it than after ligature. It is very well epithelial cancer of the larynx and trachea. The pecuknown that secondary hæmorrhage, from some peculiarities of the case were; that the man had very little liarity of the constitution, does not form a firm pain and was able to swallow liquids within three hours enough clot before the ligature separates. Then, again, it of his death without difficulty. occurs as the result of ulcerations of the arteries pre

DR. PARKER could not understand how the fluids

TION.

which the patient swallowed during the last hours of NEW YORK MEDICAL JOURNAL ASSOCIAhis life could get into the stomach, that is, if the free communication between the oesophagus and trachea, as shown in the specimen, existed at the time.

DR. KRACKOWIZER was of the same way of thinking. DR. ROGERS believed that there must have been left between the two tubes a thin partition of connective tissue, which was necessarily destroyed at the time of the post-mortem examination. He thought also that the results of the laryngoscopic examination foreshadowed the case as one of cancerous disease.

DR. BRADLEY thought that it was altogether probable that the thin partition referred to by Dr. Rogers existed before the post-mortem examination was made.

FATTY DEGENERATION OF DIAPHRAGM, ETC.

STATED REUNION, FRIDAY, JANUARY 24, 1868. DR. ISAAC E. TAYLOR, VICE-PRESIDENT, in the Chair. DR. SAMUEL D. MOSES read a résumé of the diagnosis and treatment of Uterine Displacements. The paper laid no claim to originality, but gave a concise yet comprehensive statement of the views held by the best authorities.

DR. PEASLEE, after speaking of certain methods of manipulation, said he had been glad to hear the statement that mechanical support is necessary, as a general rule, in the treatment of uterine displacements. It is as DR. FINNELL presented a portion of a diaphragm which indispensable here as are splints for fractures. Some had been subject to fatty degeneration, with a view of uterine malpositions, like some fractures, may be treatobtaining the opinion of some of the members in regarded without support, but others cannot be; and when it is said that the proper treatment is to remove the cause, the remark is as appropriate with reference to fractures as to displacements.

to its being an element in the production of sudden death. It was removed along with a fatty heart from a woman 50 years of age, who was seemingly as well as usual, lay down in the afternoon and was found dead in the evening. He next exhibited a calcified tuberculous bronchial gland, and also a hydrocele from the right side which presented the peculiarity of having the testicle adherent to the left side of the sac, which circumstance would have insured the wounding of that organ if the operation of tapping had been performed.

DR. WYNKOOP exhibited an appendix vermiformis which has already been published.

ELEPHANTIASIS OF CLITORIS.

DR. MASON exhibited a specimen of elephantiasis of the clitoris removed from a patient of the Charity Hospital. She was about 30 years, and had been suffering from constitutional syphilis. The tumor had commenced to grow about five years ago and had gradually increased until, at the time of its removal, it weighed two ounces and a hundred grains. It measured four inches in length and four and a half inches around its largest circumference. The removal was effected by the écraseur. Two large arteries had to be tied, and some oozing which persisted had to be controlled by actual cautery.

The nymphæ were not involved in the disease, a circumstance which was, by the way, remarkable.

DR. MESSINGER exhibited a portion of the falx cerebri containing a bony deposit, for the sake of ascertaining if it had anything to do with the cause of death in the following case:-A patient having suffered previously with pain in the mastoid process and discharge from the ears, which, by the way, was treated with cups and leeches, received a playful blow upon one side of his face, causing him a great deal of extra pain. This was followed by chills, which continued for four or five days at irregular intervals, when he was seized with the declared symptoms of meningitis, from which he shortly after died.

At the post-mortem examination there was found a good deal of effusion at the base of the brain and in the cavity of the ventricles. The point, however, to which the reporter wished to call the attention of the members was, the existence of bony plates of deposit on the upper surface of the brain in the neighborhood of the longitudinal sinus and falx cerebri. He wished to inquire if the appearance of such a concretion, which was true bone under the microscope, had anything to do in directly causing the inflammation which led to the death of the patient.

DR. PARKER did not think it had.

DR. FINNELL remarked that similar deposits of bone were often found in healthy brains in the substance of the falx cerebri or the tentorium. Adjourned.

DR. BOZEMAN'S SPECULUM.

DR. POST stated that he had been present, a fortnight before, at an operation for vesico-vaginal fistula performed by Dr. Bozeman, with the employment of his new speculum and "thoracic rest.' (Vide MED. RECORD, vol. 2, p. 481, Jan. 1, 1868.) The position upon the knees, with the chest supported by a frame, was one of exceeding comfort to the patient and convenience to the operator; and the speculum brought the parts very fully into view.

DR. HUBBARD and DR I. E. TAYLOR both endorsed Dr. Post's estimate.

DR. BOZEMAN said that he had now used the supporting frame in five cases, and always with entire satisfaction. It had been his object to devise an apparatus which should not only place the patient in the best position, but should also firmly secure her there. Anæsthetics could be readily and safely administered in this position. He had recently kept a patient thus under chloroform for an hour and a half. The speculum he had used three times, and it had fully met his expectations. In one case the vagina was the largest he had ever seen; in another it was very short and constricted, the fistula being in the bas-fond of the bladder and complicating the cervix uteri. The speculum was thus far only completed in gutta-percha. When properly made, in steel, it would be exhibited to the Association. [This was done at the meeting of March 13th, 1868, when Dr. B. described the instrument substantially as in the article above referred to, and gave a detailed history of the steps by which he had perfected it.—ED.]

STATED REUNION, FRIDAY, JANUARY 31, 1868.

DR. ISAAC E. TAYLOR, VICE-PRESIDENT, in the Chair.

ENDOSCOPY.

DR. ROBERT F. WEIR read an extended résumé of the history of the endoscope and its additions to our knowledge, especially in urethral pathology; giving also the results of his own observations. As the paper is to be published, we confine ourselves to a brief abstract. The subject was illustrated by the exhibition of several varieties of the instrument, and numerous water-color drawings of normal and morbid appearances.

[Our readers will find the endoscope figured and described on page 50, vol. I., of the RECORD, in a paper by Dr. Van Buren] Both as originally devised by Desormeaux, and as modified by Cruise, of Dublin, the instrument required one hand of the operator to hold the lamp connected with it, or it was placed on an un

wieldy stand. Dr. Weir had obviated this inconvenience by attaching to a common table-lamp (burning camphorated kerosene, as in Cruise's apparatus) a Tobold's condenser, and reflecting into the tube the light received from this, by means of a Troltsch's ear-mirror, which might, if desired, be fastened to the head, as in laryngoscopy.

Desormeaux describes the mucous membrane of the healthy urethra as smooth, polished, and of a pale pink color. Its longitudinal ruge are plainly seen radiating from centre to circumference of the open end of the endoscopic tube; and the absence of this appearance indicates loss of contractility from disease. The prostatic portion has a deeper color, and shows a less regular radiation of its folds; the veru montanum and the orifices of the ejaculatory ducts are not generally observable, owing to the distension produced by the instru

ment.

vermicular contraction, apparently passing towards the
bladder, and he thus explained the tendency of foreign
bodies in the canal to pass into the bladder. Mr. Henry
Thompson (Lancet, Oct. 27, 1866) gave as the result of
his own, apparently trustworthy, observations, that this
vermicular motion was in the reverse direction, from
the bladder outward. Dr. Henry Dick (Lancet, Nov.
24, 1866) had discovered granular urethritis but two
and a half inches from the meatus; he had also employed
the instrument in the removal of a urethral polypus.
In this city the endoscope had been used by various
persons, among them Drs. Bumstead, Gouley, and Lee.
Dr. Bumstead had successfully treated, by its means,
several cases of granular urethritis. Dr. Gouley had
employed it in eight cases of the same affection; also in
impassable stricture, and in internal urethrotomy, where
he had been led to substitute for Desormeaux's urethro-
tome one of his own invention; he saw no advantage,
however, in endoscopic urethrotomy. Dr. Weir's own
experience comprised three successful cases of granular
urethritis, in which he had found the granulations
smaller than represented by Desormeaux; several cases
of spermatorrhoea dependent on congestion or inflam-
mation of the prostatic mucous membrane, in one of
which he had observed an enlarged veru montanum;
many cases of organic stricture where the mother-of-
pearl appearance was noticeable; two of impassable
stricture overcome by aid of the instrument, the diffi-
culty being due to false passages produced under
other hands; a case of scrotal fistula healed by its means,
and two cases of the effect of Holt's dilator, one of them
still under treatment, whose appearances were beauti-
fully figured; also observations on the effect of internal
urethrotomy, and on that of lithotrity upon the urethral
and vesical surfaces.

In acute gonorrhoea it is commonly unwise to introduce the tube, and Desormeaux had never examined a case before the eighth day. The mucous membrane had then lost its polish, was intensely injected, thickened, and superficially ulcerated. Dr. W. had been able to examine a urethra within twenty-four hours after the appearance of the discharge, with similar results, except that the ulcerations were absent. The endoscope reveals diagnostic differences between this specific urethritis, and the traumatic, herpetic, and catarrhal forms. The progress from gonorrhoea to gleet is like that from acute to granular conjunctivitis. The granular condition of the mucous membrane, once established, keeps up a subacute inflammatory action in this membrane and its subjacent areolar tissue, which leads to contraction and stricture. Desormeaux divides urethral stricture into three stages: 1. The acute inflammatory, seen in gonorrhoea. 2. The chronic inflammatory, with mucous membrane granular and tumefied, and the subjacent tissue also swollen. 3. The organic or inodular, where the tissues have a cicatricial, even cartilaginous hardness; their vessels have disappeared, and, probably, in consequence of this, their granulations also; and the surface presents a pearly grayish appearance. These changes may be comparatively rapid or very slow. Desormeaux found, in one case, a stricture only in the second stage, though caused by an attack of gonorrhoea forty-treating urethral granulations. He thought its value seven years before. unquestionable, but somewhat limited by difficulty of manipulation. He had been unable, as yet, to introduce the tube into the bladder.

In the treatment of these conditions the endoscope gives a precision and facility otherwise unattainable, the eye guiding the hand to make applications, through the instrument, directly to the affected part. It is of value in urethrotomy; and in some strictures of peculiar form it has proved an indispensable aid to the passage of a bougie, when without it resort to perineal section or puncture of the bladder would have been inevitable. Its uses, as shown by Desormeaux, in perinæal fistula, in various affections of the prostatic urethra, and in spermatorrhoea, were touched upon; and the synopsis of this writer's work was concluded by an account of his results in examination of the bladder, about one-half of which is opened to inspection by the instrument. Among other interesting observations, an encysted calculus had been detected, and the diagnosis confirmed by autopsy.

Cruise's observations generally corroborated those of Desormeaux, and added some points of value. He had used the instrument also in examination of the pleural cavity, through a fistula left after empyema. The Lancet for Sept. 29, 1865, contained observations on the use of endoscopy in connection with lithotomy and lithotrity, by Dr. T. P. Teale, Jr. In the same journal, for Oct. 13, 1865, Mr. Christopher Heath stated that he had discovered in the walls of the healthy urethra a constant

In conclusion, he regarded the endoscope as of positive value in the pathology, diagnosis, and treatment of genito-urinary diseases; especially in the detection of urethral chancre; in the recognition and treatment of granular urethritis (including spermatorrhoea of local origin); in the passage of such strictures as occasionally fail the best surgeons; and to a certain extent in the diagnosis of vesical calculi.

DR. STEIN had used the endoscope successfully in

DR. C. C. LEE could endorse the last speaker's remark about the difficulty of introducing the abruptly bent tube of Desormeaux into the bladder; and though he had often done it, yet it was always with pain to the patient, and he thought also with more or less damage to the urethral canal. A modification of the tube, by Warwick of London, described in Brit. Med. Jour. for August, 1867, rendered it easier of introduction, and gave a wider field of view. The application of the light in Warwick's apparatus was also peculiar, ordinary daylight being condensed by a conical metallic reflector, attached at right angles to the main tube, and having at the base of the cone a powerful convex lens. For artificial light the speaker considered Dr. Weir's apparatus an improvement upon Cruise's, and superior to any he had yet seen. As to the medical value and applicability of the endoscope, they would soon be as well established as those of the ophthalmoscope and laryngoscope; and as the instrument became more simplified, its use would rapidly extend. Desormeaux's invention was cumbersome, and though excellent for class demonstration, was hardly fit for everyday use. wick's was much lighter and more convenient. Vesical examinations were necessarily the most difficult

War

demanding great care and gentleness. In cases of stone, where the calculus was moderately large and the bladder tolerably full of fluid, Dr. Lee had found little difficulty in making out the outlines, though he had been unable to satisfy himself in regard to the size. But it was in the study of urethral disease that the instrument found its greatest use; and upon this he had nothing to add to the paper of Dr. Weir.

DR. WEIR stated that a translation of Desormeaux's work, by Dr. Hunt, was to be found in the Chicago Med. Journal of this year.

A NEW BATTERY.

DR. ROCKWELL presented a galvanic battery made by Chester, of Prince street. The cells are of glass, in which zinc and carbon plates are suspended above a solution of bisulphide of mercury. The apparatus exhibited comprised twenty cells, which by a simple contrivance could be inverted, thus immersing the plates and setting the battery in action. The advantages claimed for it were its compactness, portability, and readiness for instant use; its great power, as shown by satisfactory tests; and the length of time (several months) during which it would retain its efficiency without recharging.

STAPHYLORAPHY.

Original Lectures.

CLINICAL LECTURES ON DISEASES OF THE
GENITO-URINARY ORGANS.

BY PROF. W. H. VAN BUREN, M.D.,

CHARITY HOSPITAL.

APRIL 1, 1868.

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We have here a case of "mucous patches" in a young girl of 20, and I show you the case, because they occupy one of the rarer localities of this form of cutaneous syphilis, viz. on the under surface of the breast, and the corresponding surface of the integument of the trunk, on both sides of the body. These patches, like other syphilides, affect both the skin and the mucous membranes, but they take their designation as "mucous patches, because a serous discharge is secreted from their surfaces. Most frequently developed near the outlets of the mucous canals, as in the mouth, around the anus, especially in the neighborhood of the vulva in the female; they also affect by preference those localities on the external integument where two cutaneous surfaces are in habitual contact, as in the case before you. The housesurgeon will show you that she has them also in the cleft of the buttocks around the anus. Their discharge is offensive in its odor, and this is mainly due to the large number of sebaceous follicles developed in the regions where friction takes place habitually between adjacent cutaneous surfaces, these sebaceous follicles being the seat of the odoriferous secretions of the human body. They are found sometimes between the fingers and toes. In this case they are present also at the angles of the mouth, on the sides of the tongue, and around the tonsils, presenting the appearance of whitish patches, sometimes called "milk-spots," and looking as though the parts had been recently touched with nitrate of silver.

DR. WHITEHEAD presented a private patient, a young woman some twenty-five years of age, upon whom he had operated for congenital cleft palate. The fissure had been large, involving both the soft and hard palate, extending forward to the front teeth, and measuring seven-eighths of an inch in width. After three operations he had succeeded in completely closing the fissure in the soft parts, and in considerably diminishing that of the hard palate; so that the patient could now speak more distinctly without an obturator than she had before done with one. The great extent of the chasm had made the operations difficult. The last had been more successful than those preceding it, owing to the Doctor's having passed the wire sutures at a considerable distance from the pared edges; making them very This form of syphilis belongs to the earlier varieties numerous; removing them but two or three at once; of skin eruptions, and when the patches occupy the exand renewing when necessary. The staphyloraphy ternal integument they yield promptly to treatment. proper was then complete; but the effort at uraniscop- This girl is getting well rapidly by washing her sores lasty, that is, closure of the opening in the hard palate, with a weak solution of chloride of soda, which also had, thus far, partially failed, having been attended with neutralizes their offensive odor, and drying, and dustalarming hæmorrhage and some sloughing of the flaps. ing them with calomel, which should be diluted with The operation attempted, and which the Doctor pro-rice-flour. She is taking internally a pill composed of posed again to try, is that known as Langenbeck's, blue mass with one of the dried sulphate of iron. The which consists in dissecting up the mucous membrane ure of iron in some forms, with small doses of mercury, and periosteum from the alveolar process on each side, for the syphilis of women, is an excellent plan of treatsliding them towards the centre, and uniting by sutures, ment, for they tend strongly to become anæmic and -the fissure being ultimately closed by new bone chlorotic under the deteriora ing influence of the poison, developed by the transplanted periosteum. which has been proved to directly diminish the relative proportions of red blood corpuscles.

DR. JAMES H. ARMSBY, of Albany, has been presented by the trustees of the Albany City Hospital, with a splendid service of plate, for his ceaseless diligence in soliciting subscriptions for the improvement and enlargement of the said institution. We are happy to announce such a grateful recognition of valuable services.

Ar the University of Michigan, in consequence of the appointment of a homoeopathic professor to the faculty, Professors Ford, Armor, and Green have tendered their resignations. The remainder of the regular professional corps will probably follow suit.

DR. LUDWIG TURCK, of Vienna, the distinguished laryngoscopist, died at Vienna on the 25th of February, of exanthematous typhus, at the age of fifty-six.

But mucous patches in the mouth do not get well so readily. They reappear in this locality in successive crops, often with great obstinacy, especially in smokers, in some cases outlasting all other manifestations of the them with the solid sulphate of copper, the persulphate disease. I think I have seen benefit from touching of iron, and chlorate of potassa. It has been asserted that the secretion of mucous patches is contagious, and capable of conveying the disease. I have little doubt of this; but in many cases cited in proof of the fact, it is probable that an infecting chancre, slow in healing, has become gradually converted into a mucous patch contemporaneously with the appearance of the earlier eruptions of the skin, and the poison from this source has been ascribed to the mucous patch, when in reality it was due to the unhealed chancre.

In the next case, a young woman of twenty-two,

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