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with a brownish fur: appetite gone. Pulse was rapid and feeble,-urine and fæces passed naturally. The lungs were examined, and presented nothing more than emphysema. There was an opening two inches below Poupart's ligament, deeply excavated, with unhealthy and irregular edges. The floor of the opening was deeply undermined, formed by the adductor muscles of the thigh, and destitute of granulations. The opening passed upward and seemed to pass under Poupart's ligament. The discharge was large in amount of a thin unhealthy pus, and very offensive odor. The spine was carefully examined, and found normal. The right leg, thigh, and hip, from its attitude and general appearance, presented nothing abnormal, and she moved it as she did the other, turning in bed without pain. As there were no symptoms pointing to diseased hip, it was not examined. There was no unnatural fulness of the abdomen, no tympanites, and no tenderness complained of. Her condition was such that no other organs were examined. She complained at this time of nothing but weakness. Bed sores had already appeared on the sacrum. A solution of carbolic acid was applied to the opening with a graduated compress, secured by a spica bandage. She was given quinine, stimulants, beef-tea, beef-steak, eggs and milk. She, however, partook of it with a great deal of reluctance, as in fact she did of all other ar ticles.

April 29.-Patient in a very poor condition; vomits nearly all her food; wound looking more unhealthy and the discharge increased in amount.

May 2.-Patient a little better, is able to retain her food, but requires a great deal of urging, and then takes it as quickly as possible.

its pelvis was found enormously dilated-the infundibulæ large and distended, the papilla absent, and the calyces flattened and most of them absent. The pyramids were flattened, encroaching upon the cortical substance, and the cortical substance quite thin. On section being made and examined microscopically, the pyramidal portion was in some parts destroyed, in other parts contracted, and was fatty and granular. The uriniferous tubes were denuded of their epithelium, and covered with oil globules and granular matter; in other parts the epithelium was in each, but fatty and granular. The convoluted tubes were many of them broken down, their intervals filled up by connective tissue and débris of collapsed and ruined structures. In other parts they were denuded of their epithelium, and filled with oil globules and granular matter. Where the epithelium was not removed, they were fatty and granular-in no part were they found normal. The Malpighian bodies were in many places absent, in other parts near the surface they were enlarged, lying in unnatural proximity, and enveloped by condensed fibrous tissue; their intervals filled up by granular matter, and débris of renal structure. The left kidney was enlarged and in an advanced stage of fatty degeneration, but its ureter normal. The surface of both kidneys was smooth, their capsule thin, transparent, and adherent, so that it could not be peeled off without tearing the glandular tissue. The bladder was distended with urine, and was firmly adherent to the uterus. The uterus and surrounding vagina were the seat of epithelial cancer, which had also ulcerated into the bladder, so as to partially obstruct the ureter on the right side. The uterus was bound down to the rectum May 5.-Patient failing rapidly; general surface of and pelvis by firm adhesions, and pus infiltrated bebody cold; appetite entirely gone; tongue dry and tween its meshes. The soft tissues around the ilium furred, lips cracked, sordes on the teeth, subsultus tendi- were affected by the malignant disease, and the ilium Patient unable to answer questions, and in a and body of ischium, pubes, and acetabulum, were also semi-unconscious state. Died May 6, 8 A.M., of as- found involved. On dislocating the right femur, the acetabulum was found perforated, and the head and Autopsy 51 hours after death; rigor mortis disap-neck eroded. The opening below Poupart's ligament peared; cadaver excessively emaciated; dura mater adherent to the skull; more than natural amount of serum in the lateral ventricles; heart normal; old adhesions over the right pleura; both lungs emphysematous in all their lobes; superficial fibrous induration at both apices; old adhesions between the liver and intestines, and abdominal wall, on the right side, with evidences of old peritonitis over the whole peritoneal cavity; liver weighs two pounds, ten ounces; spleen softened, but otherwise presented nothing abnormal. The intestines were firmly agglutinated together. The ileo-cæcal valve, the cæcum, ascending colon, ilium, and part of the jejunum, were bound together by firm adhesions, and on separating them pus freely escaped. The adhesions at this point were also very marked, not only to the intestines, but to the abdominal walls. On the left side there were adhesions, though not to such an extent. The sigmoid flexure, with the rectum, was bound down and pus infiltrated between the meshes of the adherent bands. The mesenteric glands were enlarged, and many of them contained purulent fluid. The kidney on the right side was much enlarged, being nearly twice its natural size, and pushed out of its position, upward, so that it was behind the right lobe of the liver. The ureter on that side was enormously dilated, and firmly adherent to the intestines by old adhesions. On dissecting the ureter carefully down to the bladder, it was found partially occluded at its entrance into the bladder, by new tissue. An opening was made into the ureter, above its entrance into the bladder, and a fine bristle passed into the bladder with some difficulty. On cutting into the kidney,

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was found to extend upward beneath the ligament, along the course of psoas and iliacus muscles, which were thoroughly disintegrated, and far advanced in fatty degeneration.

The points of interest in this case appear to me as follows:

1st. The development of cancer to such a general extent, in so limited a time, for three months previous the patient states that she was in good health.

24. The extensive disease of both kidneys in the midst of an exhaustive disease, without giving rise to any symptoms of uræmia.

3d. The destructive disease of the pelvis, involving the acetabulum, and perforating it without any symptoms referable to that part; at the time of admission, the patient being able to walk around the ward.

PROFESSOR FICK, of Zurich,,has accepted an invitation to the chair of physiology in the University of Wurzburg.

TREATMENT OF GUN-SHOT WOUNDS IN 1514.-The first published work on gun-shot wounds bears the date of 1514, its author's name being Antonio Ferri, physician to Pope Paul III., and its title De Sclopetorum sive Achibursorum Vulneribus. From these pages we learn that the orthodox treatment for gun-shot injuries was to pour into the wounds boiling oil. The method of performing amputation was somewhat novel. The part to be removed was simply chopped off by a hatchet, and the bleeding checked by the application of a red-hot iron to the stump.-London Medical Mirror.

Original Lectures.

ABSTRACT OF A LECTURE UPON

THE THERAPEUTICS OF WAKE-
FULNESS:

DELIVERED AT BELLEVUE HOSPITAL MEDICAL COLLEGE,
BY WILLIAM A. HAMMOND, M.D.,

PROFESSOR OF DISEASES OF THE MIND AND NERVOUS SYSTEM.

BRUSHING the hair, or friction of the skin, as by rubbing the palms of the hands or the backs of the arms, will in some persons tend to induce sleep. Soothing sounds have sometimes a similar effect. On the other hand, persons whose occupations are noisy are apt to awake when the noise to which they are accustomed suddenly ceases. A miller has been known to wake up when the noise of the machinery stopped, and a man, who had for many years lived within sound of the roaring of Niagara Falls, was unable to sleep at first on removing from the locality.

But agents more efficacious than such external ones, are those which lessen the amount of blood circulating in the brain. First may be mentioned food and drink, of whose happy influence a frequent illustration is given in the case of a late supper. During digestion more blood circulates through the gastro-intestinal vessels than when the abdominal organs are unemployed; and this additional amount of blood must come from some other part of the body, since a marked excess of this fluid cannot exist in two different parts at the same time, except in cases of disease. That the amount of blood in the brain is diminished during digestion is evinced by the feeling of drowsiness commonly experienced, which is a perfectly healthy sensation. The food, thus taken as a therapeutic agent, should be easily digestible. The sensible physician will hardly resort to drugs, if such pleasant medicine as a good supper can be given with equally good effect.

In persons weak or anæmic, especially women who have been rendered so by hæmorrhages, a dose of some one of the various preparations of alcohol at bedtime is frequently advisable. Of these, wines are not generally so admissible as the stronger preparations, such as spirits; in this country whiskey will be most easily attainable. A Methodist clergyman, who came under my care, had been unable for seven or eight weeks to sleep more than two hours each night. I prescribed a dose of whiskey to be taken at bedtime. He at first strongly protested against taking it, upon grounds of principle and his previous habits of total abstinence, but finally agreed to try the remedy. The first night he slept five or six hours, the second, seven or eight hours; his whiskey was then reduced in amount gradually, from half a glassful to none at all. He continued to sleep well, and had not formed any habit of drinking.

In healthy persons, coffee is calculated to produce wakefulness; in others it acts as a hypnotic, much as other stimulants do in asthenic cases. For the latter purpose, do not trifle with it by administering a little of a weak infusion, but give strong doses at once. Much depends upon the method of making it. Exhaust the strength of three or four ounces of ground coffee by percolation, with a rather small amount of boiling water; and give without milk or cream. Tea is not to be compared with coffee as a therapeutic agent, in this connection. It acts in a similar manner, but not so efficiently.

Sometimes sleep may be produced by physical exercise taken regularly about two hours before bedtime. This acts best in sthenic cases. It has been often noticed that change of air and carriage exercise produce sleep. The modus operandi of this I cannot explain, any more than the familiar fact that the rocking of a cradle puts an infant to sleep.

Some time ago, in England, there was constructed a table, known as Darwin's table, for the purpose of producing sleep in the insane. It was circular, and rotated upon a screw at the centre. On this the patient was placed, with his head at the centre, and the table was turned, thus producing sleep according to correct physiological principles, although those principles were not then known.

The warm bath may be used as a hypnotic. In employing it, the head should be prevented from becoming heated, as by putting cold water upon it while the body is immersed; the application of cold water_is, however, rarely necessary in the case of infants. The temperature of the bath is best regulated by the hand. Sometimes cold water alone applied to the head proves sufficient, without the warm bath. I remember having read somewhere in Graves' writings that the Indian women sometimes put their babies to sleep by giving their heads a cold douche; this was also applied in the British army at one time as a punishment, and, it was found, with the almost invariable effect of producing sleep."

Another remedy, often of much value, is the application of a sinapism to the epigastrium. How it acts I do not know; it cannot well do so through the circulatory system, but may by impression upon the nervous system.

The position of the body is important. In many cases, holding the head down produces wakefulness; such persons should, in case of wakefulness, go to sleep in the erect position.

Certain drugs form another class of agents for the production of sleep. That which has been longest in use is opium. As regards its power of bringing on sleep, the dose of opium varies in different patients. In small doses of half a grain to three-fourths, as an average, it acts as a stimulant; in moderate doses of one or two grains, it is hypnotic; and in larger ones it produces stupor, and not true sleep. Narceine, one of its constituents, has been found to produce profound and continuous sleep, but the ordinary preparations of it are too uncertain to be relied upon, and it is too expensive for frequent use.

Hyoscyamus sometimes acts excellently; it has the advantage over opium of not producing headache and constipation the following day. The tincture, especially Neergaard's, may be given in doses of a drachm to a drachm and a half three times a day, if necessary.

Oxide of zinc may prove serviceable in some cases. It came into use in the treatment of the nervous condition preceding delirium tremens. It has also been of value in hysteria when everything else has failed. Its dose is, as a maximum, two grains three times a day; as much as four grains may be given at the same intervals, but this quantity will generally produce irritability of the stomach.

Phosphorus is a remedy which has come into use more recently, in the class of cases of which we are speaking. It is supposed to act by supplying a deficiency in the elements of nervous tissue, increasing the amount of protagon. Owing to its chemical properties, it is not easily administered. It can be given in the form of phosphorated olive oil, in the proportion of four grains to the ounce. It is preferable, however, to boil twelve grains of phosphorus in one ounce of

almond oil, and filter. The oil absorbs four grains of phosphorus, so that each minim contains 1-120 of a grain. Half an ounce of the oil is now mixed with an ounce of gum arabic, and fifteen drops of some aromatic oil are added. Of this mixture the dose is fifteen drops, equal to five drops of the phosphorated oil, and containing 1-24 of a grain of phosphorus. I have used this remedy in eight cases with success, and failed in two cases. I try to get three doses taken before bed-time, and thus far have generally succeeded in producing the desired effect on the second day, if I had not on the first. The dose may be increased a drop a day, till twenty drops are taken, or signs of gastric irritation supervene. I would not advise giving it in larger doses. In one of my cases, nausea was produced on reaching twenty drops, but sleep ensued also. But of all the sleep-producing agents at our disposal, the bromide of potassium is most deserving of the name of hypnotic. I have never seen it fail when given in sufficient quantity. A healthy adult may take from twenty to thirty grains three times a day; the latter dose is not too large when it is needed at all. Sometimes it produces, among its other effects, great weakness in the legs, and a staggering gait, strongly resembling that of a person intoxicated with alcohol. In fact, I know of a gentleman who, while under the influence of this drug, was twice arrested in our streets for drunkenness. Bromide of potassium occasionally produces also great lowness of spirits and a disposition to cry. It should be administered very much diluted. It may be conveniently prescribed one ounce to four ounces of water; a drachm dose of this to be given

in at least half a tumblerful of water.

A remedy which I have used recently, especially in cases of nervous excitement where a sedative seemed indicated, is sumbul. This is a plant of the same family as valerian. I have used it in conjunction with bromide of potassium in epilepsy, with the result, as I think, of increasing the effect of the latter. The dose of the fluid extract (Neergaard's) is from twenty drops to a drachm three times a day.

Progress of Medical Science.

with a towel, and the leg of the affected side flexed on the abdomen. Mr. I. grasped the tumor, and I dashed the cold water (above a pint) suddenly over the thoracic and epigastric regions. The patient gave a quick and deep inspiration, and the hernia slipped up into the abdomen. The man did well.”

L'Union Médicale for August records from the Annales INTESTINAL OBSTRUCTION CURED BY ELECTRICITY.de la Société de Médecine de Gand, the case of a woman of sixty-eight years of age, attacked by colic, with retention of fæces. Injections and purgatives were with considerable tympanites, unaccompanied by limadministered without result. Finally vomiting set in ited points of tenderness on pressure. Dr. Hephel resorted to nux vomica. The age of the patient, her slowness of movement, her state of temper, with entire absence of pain, and the presence of an abdominal tumor, naturally led to belief in the existence of an intestinal paralysis, symptomatic of some nervous affection. Two grains of nux vomica were administered in twenty-four hours. At the same time the belly was covered oesophagian sound. The sound was introduced into with ice, and cold injections administered with the the rectum without difficulty, as far as the junction of the descending colon with the transverse colon; still, the obstruction remained constant. The meteorism increased, and stercoraceous vomiting followed the watery and bilious vomiting. Prostration, alteration of countenance, irregularity and slowness of pulse, all denoted the approach of death.

cation of electricity with the portable apparatus of It was decided in consultation to employ the appliGaiffe. An olive-shaped electrode was introduced into the rectum; the other, in the form of a moistened sponge, was applied over the belly. The application was continued for ten minutes. The electricity produced sensations of heat and pain all through the abdomen; and these sensations persisted for a long time cation was made in the evening about nine o'clock. after the interruption of the current. A second appliThe patient felt better. The following night there was no vomiting, and the next morning there was a slight evacuation of soft consistence. Electricity was again employed. A second evacuation ensued, speedily followed by a third. The peristaltic progression of the fæces once established, all the symptoms disappeared, and in a few days this woman was attending to her domestic affairs.

THE RELIEF OF PAIN IN OPEN CANCER.-The field for experience in cancer at Middlesex Hospital is, as is well known, an unusually large one, and opportunity has therefore been afforded for testing fairly the action of IODIDE OF POTASSIUM IN CHRONIC BRONCHITIS.-Dr. remedies in affording relief in this distressing disease. Clarke (Gazz. med. di Padova) obtains good effects in We learn that the exquisite pain which belongs to open cases of chronic bronchitis with irritation and tumecancer is found to be best relieved by the stramonium faction of the mucous membrane without secretion, by ointment, which is employed at this institution. The fol- the administration of iodide of potassium (1 décilowing is the formula for this in the hospital pharma-gramme) combined with tartarized antimony (8 millicopoeia:-Half a pound of fresh stramoniumn leaves, and two pounds of lard. Mix the bruised leaves with the lard, and expose to a mild heat until the leaves become friable, then strain through lint. The ointment thus prepared is spread upon lint, and the dressing changed three times a day.

NEW TREATMENT FOR STRANGULATED HERNIA.-A correspondent of the Lancet writes as follows regarding a case of strangulated hernia :--"The patient was put into a warm bath, and taxis again tried in the bath, without making any impression on the tumor. Mr. I., not knowing the nature of the illness when he left home, did not provide himself with chloroform or surgical instruments. He gave me directions secretly, without the patient's knowledge, to procure from one of the attendants some cold spring water from the well. This being done, the patient's eyes were covered

grammes) in water (25 grammes) holding in solution acetate of ammonia (3 grammes). This medication is to be suspended on the return of the expectoration, or when there is danger of hyposthenia. Dr. Clarke finds in the cases mentioned, that alcohol is not indicated, though it may be given when there is abundant secretion, with difficulty of expectoration. This stimulant is otherwise but rarely indicated, save in cases of old people and infants.—L' Union Médicale.

CINCHONA IN JAMAICA. It is expected that from 8,000 to 10,000 plants of the Cinchona succirubra will be ready for sale in the Island of Jamaica, at the plantation at Gordon Town, in the spring of 1869.

ETHER SPRAY is used successfully in Lyons, France, to render painless the operation of uprooting hair when necessary in cases of cutaneous disease.

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Mix in a mortar, using a spatula, and adding the oil at intervals. Thus is obtained a soft paste, semi-gelatinous, readily emulsioned when mixed little by little with water. This glycerole of almonds may replace gum, magnesia, for opiates, electuaries, &c., with castor oil, cod liver oil, copaiba, &c. Twenty-five centigrammes will emulsify forty-nine grammes of oil. A hot infusion, filtered and sweetened, affords a very useful and nutritious syrup.-Union Pharmaceutique.

CRYPTOPIONINE, A NEW ALKALOID FROM OPIUM.— Messrs. T. & H. Smith (Pharm. Journ. et Union Pharmac.) have discovered a new alkaloid in opium--Cryptopionine. We may have sulphates, muriates, azotates, thébolactates of cryptopia. This substance is colorless, inodorous, of a bitter taste, giving rise to a subsequent sensation of cold in the tongue and palate, similar to that produced by peppermint. It is insoluble in benzine, ether, spirits of turpentine, and almost as soluble in chloroform as is narceine. Nothing is said of the physiological properties of this new alkaloid.-L' Union Médicale.

ADMINISTRATION OF BROMIDE OF POTASSIUM.-C. V. Berryman, M.A., M.D., Prof. Mat. Med., Victoria Med. College, Toronto, Canada (The Dominion Med. Journal), administers bromide of potassium in epilepsy, in doses of grs. x or xv three times a day for a month, and then increases it, say by grs. v. to each dose. In delirium tremens, grs. xxx. should be given at once, and repeated in two hours if sleep is not promoted, and after that, if awake, the dose should be administered every four hours. He has had but one case where these doses produced irritation of the bowels. In the latter affection, by this mode of procedure, his best wishes and anticipations have been realized-restorative sleep and quietude have invariably followed.

In epilepsy, all of the cases under his care at the Toronto General Hospital, with the exception of one, were controlled by its use.

PNEUMONIA OF THE APEX OF THE LUNG.-At the Hôpital St. Eugénie (The Dominion Med. Journal), cases of pneumonia of the apex have been noted by M. Barthez. Convulsions, which lasted from three to four days, marked the outset of the disease in two cases. The disease did not become apparent until the fifth day, and on the seventh, resolution had already taken place. In another child the disease assumed the character of typhoid fever, the symptoms of which disappeared when pneumonia manifested itself on the fifth day.

M. Besnier insists upon the peculiar interest of these OPERATION OF TRACHEOTOMY IN CROUP.-Dr. Krack-cases in the study of infantile pneumonia. owizer (Am. Jour. of Obstetrics) has operated by trache- ACUTE PHTHISIS AND TREATMENT.-M. Colin (The Dootomy for croup 56 times with the following results: deaths, 40; recoveries, 16.

Causes of Death.-Asphyxia during operation, 1; granulations from cicatrix, 1; infectious diphtheria, 3; exhaustion and pulmonary edema, 4; scarlatina, 1; descending croup and bronchitis, 30; total 40.

Dr. Jacobi has saved by the operation thirteen out of sixty patients.

If the operation is resorted to in the early stages of the disease, the percentage of successful cases rises as high as from twenty-seven to forty-five per cent.

minion Med. Journal) records cases of "galloping consumption" in Hôpital Val de Grâce; death ensued in one case, after the symptoms of typhoid fever presented themselves. M. Colin recommends digitalis in this disease, administered in small doses, so as to combat the fever and dyspnoea, and suspend the fatal course of the disease, at least during a certain period of time.

SUCCESS OF TRACHEOTOMY IN CROUP.-In four Paris Hospitals, in May, 1868, 19 cases of croup appeared. Tracheotomy was performed in 17 of these cases, 4 were successful; 13 of the patients died. In one case, which terminated successfully without tracheotomy, the oleoresinous extract of cubeb had been given. In 8 cases, the operation was performed by M. Barthez.

66

TREATMENT OF TYPHOID FEVER DURING CONVALESCENCE -Dr. Hudson gives the following excellent advice in the management of typhoid patients during their convalescence, in his lectures now being published in the Medical News and Library. Absolute rest must be inTHE SOLUBILITY OF DIPHTHERITIC MEMBRANES.--MM. sisted on, all stimulants prohibited, and the blandest Brichetau and Adrian (Union Pharm.) have made a numnourishment only allowed to be given. It must be ber of experiments to test the solubility of false recollected that a large proportion of cases of perfora- membranes" in various medicinal substances; and antion of the intestine occur during this period. Coun-nounce, among other things, the following results:ter-irritation by means of small blisters, or by tincture of iodine, should be employed, if there is protracted diarrhoea, or pain and tenderness on pressure over the cæ cum. Avoid irritating purgatives; the bowels should be opened every third day by an enema of warm water, or perhaps, occasionally, by a small dose of calomel, or gray powder combined with opium.

To improve the condition of the intestinal ulcers and of the mucous membrane, nitrate of silver and the turpentines are the most worthy of the confidence of the physician. Poultices to the abdomen are important in this stage.

CAUTERIZATION OF HEMORRHOIDS.-Mr. Henry Smith, of King's College Hospital, London, treats hæmorrhoids and prolapsus of the rectum by seizing the tumors with a clamp, cutting them off with scissors, and cauterizing the bases with the hot iron. Numerous cases of cures by this method are reported.

The dry residue of a nut, &c., after extraction of the oil.

A false membrane maintained for an hour in the midst of vapors of sulphate of mercury is not dissolved; it is only softened as by vapor of water; retained in a concentrated solution of pepsin maintained at a temperature of 30° C., it is not dissolved but at the end of 12 hours; but if 6 to 10 drops of lactic acid be added to the pepsin, the solution is accomplished at the end of 8 minutes. Caustic acids (hydrochloric, sulphuric, azotic) do not dissolve false membranes. Acetic acid renders the diphtheritic membrane transparent, gelatinous, but does not dissolve it completely. Citric acid produces a similar effect. Lactic acid, in the proportion of brane of the weight of 20 centigrammes in 3 minutes. 2 drops to 5 grammes of water, dissolved a tough memWith lime-water, the effect is still more rapid; lactate of lime is without action. Water alkalinized by soda and better than their concentrated solutions. Bromine or potassa, dissolves the membrane in 8 or 10 minutes, water, and bromine in statu nascente, only disintegrate the membrane; bromide of potassium has no apparent

action; salts of soda and potassa, such as sulphate of soda, sulphate of potassa, the bicarbonate, nitrate, &c., are without action, as also chloride of zinc, and chromic acid. The chlorates of potassa and soda dissolve membranes, but slowly.-L' Univ. Med.

CEANOTHUS AMERICANUS.-Dr. D. L. Phores (Atlanta Med. and Surg. Journal) recommends the use of this drug in splenitis; and so well satisfied is he of its efficacy, that he has used nothing else for enlarged spleen. He says: "In this affection I have never found any remedy superior to Ceanothus Americanus. I have yet to hear of its failure in a single case, however inveterate." He uses it in the form of a tincture, and gives it in doses of from 3 ss. to j three times a day. He directs it also to be rubbed over the region of the spleen twice a day.

ity, but still-born. It bore the mark of the fire corresponding to that of the mother. Its legs, arms, and abdomen were completely vesicated, having all the appearance of a recent burn.-Nashville Journal of Medicine and Surgery.

ASTHMA.-Dr. Begbie cured two cases of asthma of long standing, where the patient had renounced all hope of benefit from drugs, by the use of bromide of potassium in free doses morning and night.-Iumboldt Medical Archives.

BROMIDE OF POTASSIUM AND ANTIMONY IN PUERPE violent puerperal convulsions, in which the inhalation RAL CONVULSIONS.-Dr. T. N. Simmons reports a case of of chloroform had failed, cured by brom. potass. and tart. ant. et pot., 40 grs. of the former and gr. of the latter at first, and then 10 grs. bromide with gr. ant. every hour or two until six doses in all had been taken. The convulsions gradually subsided, and convalescence was rapid. He recommends the same combination in delirium tremens, sometimes adding a small quantity of morphia.-Phila. Med. and Surg. Reporter.

INGUINAL HERNIA STRANGULATED BY AN ARTERY.

IDIOPATHIC TETANUS IN JAMAICA.-Dr. F. D. Lente, in a communication to the N. Y. Med. Journal, says: "This disease is very common in Jamaica and other West India islands. It is generally induced by sudden chilling of the body or suppression of perspiration. The mortality, compared with that of the traumatic variety, is not great; though it presents all the terrible suffering of the latter. The traumatic form is also very Dr. John Cleland reports in the British Med. Journal, common, and follows the most trivial accidents. Two a case of strangulated inguinal hernia, in which the remarkable cases occurred at Horowa, on a plantation cause of the constriction was found to be an artery, near Matanzas. Two little negroes, brothers, had each probably "an obturator artery, arising from the epigasgot a chigoe' in the toe, and the mother, as usual, tric, and arching upwards in its course, or by a common opened the sac with a needle, and pressed out the trunk of unusual length, from which the obturator and animal, filling the cavity with some simple preparation. epigastric arteries were given off nearer the middle Both were attacked the succeeding day with tetanus. line." The vessel was first ligated in two places, and Within three days one had died, and the other recovhen cut between the points of ligation; the strangulaered only after a severe illness." Bright's disease is ion was at once relieved, and the patient ultimately very common in Jamaica, and appears to be on the in-ecovered.-N. O. Journal of Medicine.

crease.

CARBOLIC ACID IN CUTANEOUS DISEASE. - Dr. F. P. Mann (New York Medical Journal) cal's the attention of the profession to the efficacy of carbolic acid in the treatment of diseases of the skin, particularly those which are known to depend upon or are accompanied by the development of fungi. He reports three cases; one of chronic eczema, one of impetigo, and one of psoriasis inveterata. In the former case the incrustations covered the head and entire trunk and limbs. The secretions were intensely acid. By a course of alkaline treatment the improvement was rapid, but fresh groups of eczema pimples continuing to be reproduced, carbolic acid, of the strength of 3 83. to water iv., was applied three times a day. The effect was immediate, and the vesicles disappeared promptly; In the cases of psoriasis, the carbolic acid was applied in conjunction with the administration of Donovan's solution. The disease soon yielded to the treatment.

EXTERNAL USE OF LIQUOR AMMONIÆ ACETATIS.-Dr. Tolmatschen of Kason (Deutsch Klinik) has tried the local application of spts. mindereri in several cases of muscular rheumatism as well as in some cases of

pneumonia. The affected part was well bathed with the medicine and then dried. On being again covered with the usual bed-clothing, in each case the affected part broke out in a moderate perspiration, with ameliotion of the pain. The internal use of the medicine was sometimes combined with its external employment.N. Y. Med. Journal.

SINGULAR EFFECT OF A BURN.-Dr. S. P. Crawford is the authority for the following history: A lady being in the last stages of gestation, was so severely burned upon the face, body, and extremities, that she survived the accident but twelve hours. A short time before death she gave birth to the child, at full matur

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THE COUNTER-IRRITATION OF CUPS INCREASED.-Mr. E. J. Leyburn has invented a cup which increases the efficacy of cupping, as a counter-irritant. The invention consists of an adjustable irritating disk of serrated wood, which by coming in contact with the integument, under the pressure generated, establishes a harmless but very effective irritation.-Richmond and Louisville Med. Journal.

ON THE ACTION OF ACONITE AND QUINIA IN NEURALGIA.-H. M. Jones, M.D., in the Medical Press and Circular, communicates an article on this subject, in which he advocates the use of these remedies, and cites a case in which they acted promptly and gave a speedy recovery. The article concludes by saying that quinine may be used as an adjunct to aconite: 1st. In neuralgia occurring in anæmic or debilitated persons, without any nerve-lesion or exciting cause. old cases of neuralgia, where the primary disease has produced a state of the circulation at the part affected not in accordance with health. 3d. In all cases where to a temporary relief we would add permanency of cure.

2d. In

THE TREATMENT OF HÆMORRHOIDS.-The Medical Press

and Circular publishes an article from J. Mulvaney,
for hæmorrhoids. The first case which he reports was
M.D., in which he strongly urges the use of belladonna
one where the piles were internal and of two years'
standing. The tumors were large, protruded, and bled
and suffered from general debility, consequent upon
during defecation. The patient was much emaciated,
constant suffering and repeated hemorrhages.
treatment consisted in clearing out the bowels with oil,
and then in the administration of the fluid ext. of bel-
ladonna in two-and-a-half drop doses every four hours,
with lavements of cold water twice a day.
days the bleeding had quite ceased, and in ten days the
hæmorrhoid had entirely gone and did not return."

The

"In two

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