Parasites and Infectious Disease: Discovery by Serendipity and Otherwise

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Cambridge University Press, 2007 M05 31 - 355 páginas
This series of entertaining essays provides a unique insight into some of the key discoveries that have shaped the field of parasitology. Based on interviews with 18 of the world's leading parasitologists and epidemiologists, the stories of their contributions to discovery in contemporary parasitology and infectious disease biology are told. Taken together, the essays provide a historical account of the development of the field, serving as a bridge between these discoveries and current research. The book provides a real insight into the thought processes and approaches taken in generating break through scientific discoveries, ranging from immunology to ecology and from malaria and trypanosomiasis to schistosomiasis and Lyme disease. This engaging and lively introduction to discovery in parasitology will be of interest to all those currently working in the field and will also serve to set the scene for future generations of parasitologists.

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Contenido

Prologue
1
Dick Seed
3
Keith Vickerman
6
Bob Desowitz
9
K Darwin Murrell
12
Bill Campbell
18
Richard Tinsley
25
Sidney and Margaret Ewing
28
African trypanosomes and their VSGs
108
Malaria the real killer
128
The HIVAIDS vaccine and the disadvantage of natural selection the yellow fever vaccine and the advantage of artificial selection
150
Lyme disease a classic emerging disease
164
The discovery of ivermectin a crapshoot or not?
175
You came a long way to see a tree
188
Infectious disease and modern epidemiology
203
The unholy trinity and the geohelminths an intractable problem?
219

Don Bundy
37
Peter Hotez
42
David Rollinson
48
John Hawdon
53
Mark Honigsbaum
61
Roy Anderson
65
Steve Nadler
77
Jim Oliver
86
Pat Lord
95
J P Dubey
100
Hookworm disease insidious stealthily treacherous
236
The spadefoot toad and Pseudodiplorchis americanus an amazing success story of two very aquatic species in a very dry land
254
The schistosomes splitbodied flukes
265
Dicrocoelium dendriticum and Halipegus occidualis their life cycles and a genius at work
282
Trichinosis and Trichinella spp all eight of them or is it nine?
299
Phylogenetics a contentious discipline
315
Toxoplasma gondii Sarcocystis neurona and Neospora caninum the worst of the coccidians?
328
Summary
345
Index
348
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Gerald W. Esch is Charles M. Allen Professor of Biology at Wake Forest University, Winston-Salem, North Carolina, USA. He is editor of the Journal of Parasitology, the author of Parasites, People and Places: Essays on Field Parasitology (2004) and co-author of the textbook Parasitism (2001). He is a recipient of the Louis T. Benezet Distinguished Alumnus Award from his undergraduate alma mater, Colorado College, in 1992, and of the Clark P. Read Mentor Award from the American Society of Parasitologists in 1999.

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