Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We UseOxford University Press, 2006 M09 7 - 336 páginas The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful. |
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Página 16
... chain. Because of the intricacy of the Taxol structure, they initially submitted the manuscript with the side chain attached at the wrong site, although they corrected it immediately prior to publication. Because of its insolubility ...
... chain. Because of the intricacy of the Taxol structure, they initially submitted the manuscript with the side chain attached at the wrong site, although they corrected it immediately prior to publication. Because of its insolubility ...
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... chain installation process patented by Robert Holton at Florida State University to make Taxol. More than 3 tons of English yew needles, a renewable source, must be collected and processed in order to produce 1 kilogram of 10-DAB. The ...
... chain installation process patented by Robert Holton at Florida State University to make Taxol. More than 3 tons of English yew needles, a renewable source, must be collected and processed in order to produce 1 kilogram of 10-DAB. The ...
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... (Mabs) vs. Tyrosine Kinase Inhibitors R R K K R R K K Ligand Ligand the molecule with a basic 6-alkyl side (TKIs). Diagram by Vivien H. Li chain produced Iressa, which had improved in vivo activities, as 34 laughing gas, viagra, and lipitor.
... (Mabs) vs. Tyrosine Kinase Inhibitors R R K K R R K K Ligand Ligand the molecule with a basic 6-alkyl side (TKIs). Diagram by Vivien H. Li chain produced Iressa, which had improved in vivo activities, as 34 laughing gas, viagra, and lipitor.
Página 35
The Human Stories behind the Drugs We Use Jie Jack Li. chain produced Iressa, which had improved in vivo activities, as well as physical properties. Its favorable pharmacokinetic attributes allowed a once-daily oral dosing. In addition ...
The Human Stories behind the Drugs We Use Jie Jack Li. chain produced Iressa, which had improved in vivo activities, as well as physical properties. Its favorable pharmacokinetic attributes allowed a once-daily oral dosing. In addition ...
Página 44
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Contenido
3 | |
2 Drugs to Kill Germs | 43 |
From Nitroglycerin to Lipitor | 75 |
4 Sex and Drugs | 103 |
5 Drugs of the Mind | 129 |
6 Diabetes Drugs | 165 |
7 Anesthetics | 187 |
8 AntiInflammatory Drugs | 213 |
9 Reflections | 241 |
Chemical Structures | 245 |
Trademarks of the Drugs | 277 |
Bibliography | 281 |
Index | 295 |
Otras ediciones - Ver todas
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Términos y frases comunes
ACE inhibitors acid active agents alcohol anesthesia anesthetic antibacterial antibiotics antidepressants aphrodisiac approved aspirin Avastin Banting barbiturates became beta-blockers biological blood breast cancer Bristol-Myers Squibb calcium cancer drugs cause cells Chain chemical chemist chemistry chemotherapy chloroform chlorpromazine cholesterol clinical trials cocaine compounds cortisone depression developed diabetes discovered disease doses drug discovery EGFR enzyme estrogen ether extract Florey Gleevec guinea pigs haloperidol heart hormone human inhibit inhibitors initially injection insulin Iressa isolated kinase laboratory later leukemia leukotriene Lilly Lipitor lithium liver Macleod Marsilid medicine Merck metabolism mevastatin million molecule Morton nitroglycerin nitrous oxide Nobel Prize Novartis oral pancreas Parke-Davis patients penicillin Pfizer pharmaceutical Physiology production Prontosil prostaglandin protease protein Prozac receptor rheumatoid arthritis Roche scientists serotonin side effects Squibb statins streptomycin sulfanilamide Syntex synthesis tamoxifen Taxol tested therapy tion toxic trade name treating treatment tuberculosis tumors University Viagra virus Waksman