Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We UseOxford University Press, 2006 M09 7 - 336 páginas The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful. |
Dentro del libro
Resultados 1-5 de 16
Página 13
... Lilly had also made similar discoveries. In December 1957, Svoboda submitted extract of the whole vinca plant for testing. It showed a 60–80% prolongation of life for mice infected with P-1534 leukemia, an acute lymphoblastic leukemia ...
... Lilly had also made similar discoveries. In December 1957, Svoboda submitted extract of the whole vinca plant for testing. It showed a 60–80% prolongation of life for mice infected with P-1534 leukemia, an acute lymphoblastic leukemia ...
Página 14
... Lilly has marketed vincristine (trade name Oncovin) for acute childhood leukemia and vinblastine (trade name Velban) for lymphoma such as Hodgkin's disease, for advanced testicular cancer, and for advanced breast cancer. Similar to ...
... Lilly has marketed vincristine (trade name Oncovin) for acute childhood leukemia and vinblastine (trade name Velban) for lymphoma such as Hodgkin's disease, for advanced testicular cancer, and for advanced breast cancer. Similar to ...
Página 24
... Lilly as an osteoporosis drug, renders a 58% reduction in breast cancer. Today, the correlation between sex hormones and cancer has been well established. Breast cancer in particular is linked to estrogen abnormality. In 2004 hormone ...
... Lilly as an osteoporosis drug, renders a 58% reduction in breast cancer. Today, the correlation between sex hormones and cancer has been well established. Breast cancer in particular is linked to estrogen abnormality. In 2004 hormone ...
Página 30
... Lilly bought Hybritech and returned the rights of C225 to UCSD because it did not fit its business plan—oncology was not a major focus at Lilly. Subsequently, Mendelsohn spoke with many big pharmaceutical companies, but none were ...
... Lilly bought Hybritech and returned the rights of C225 to UCSD because it did not fit its business plan—oncology was not a major focus at Lilly. Subsequently, Mendelsohn spoke with many big pharmaceutical companies, but none were ...
Página 51
Alcanzaste el límite de visualización de este libro.
Alcanzaste el límite de visualización de este libro.
Contenido
3 | |
2 Drugs to Kill Germs | 43 |
From Nitroglycerin to Lipitor | 75 |
4 Sex and Drugs | 103 |
5 Drugs of the Mind | 129 |
6 Diabetes Drugs | 165 |
7 Anesthetics | 187 |
8 AntiInflammatory Drugs | 213 |
9 Reflections | 241 |
Chemical Structures | 245 |
Trademarks of the Drugs | 277 |
Bibliography | 281 |
Index | 295 |
Otras ediciones - Ver todas
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Términos y frases comunes
ACE inhibitors acid active agents alcohol anesthesia anesthetic antibacterial antibiotics antidepressants aphrodisiac approved aspirin Avastin Banting barbiturates became beta-blockers biological blood breast cancer Bristol-Myers Squibb calcium cancer drugs cause cells Chain chemical chemist chemistry chemotherapy chloroform chlorpromazine cholesterol clinical trials cocaine compounds cortisone depression developed diabetes discovered disease doses drug discovery EGFR enzyme estrogen ether extract Florey Gleevec guinea pigs haloperidol heart hormone human inhibit inhibitors initially injection insulin Iressa isolated kinase laboratory later leukemia leukotriene Lilly Lipitor lithium liver Macleod Marsilid medicine Merck metabolism mevastatin million molecule Morton nitroglycerin nitrous oxide Nobel Prize Novartis oral pancreas Parke-Davis patients penicillin Pfizer pharmaceutical Physiology production Prontosil prostaglandin protease protein Prozac receptor rheumatoid arthritis Roche scientists serotonin side effects Squibb statins streptomycin sulfanilamide Syntex synthesis tamoxifen Taxol tested therapy tion toxic trade name treating treatment tuberculosis tumors University Viagra virus Waksman