Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We UseOxford University Press, 2006 M09 7 - 336 páginas The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful. |
Dentro del libro
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Página xi
... who are tirelessly at work developing the cures of the future and for students who aspire to such a noble cause. Phil S. Baran April 2005 La Jolla, California This page intentionally left blank preface This is a book foreword xi.
... who are tirelessly at work developing the cures of the future and for students who aspire to such a noble cause. Phil S. Baran April 2005 La Jolla, California This page intentionally left blank preface This is a book foreword xi.
Página 4
... caused cancer, with one camp believing that carcinogens (cancer-causing agents such as chemicals, X-ray, and ... cause cancer in an animal model.1 In 1926, the Nobel Prize in medicine was awarded for making great strides toward ...
... caused cancer, with one camp believing that carcinogens (cancer-causing agents such as chemicals, X-ray, and ... cause cancer in an animal model.1 In 1926, the Nobel Prize in medicine was awarded for making great strides toward ...
Página 5
... cause of lung cancer.3,4 During World War II, the Nazis waged a campaign against smoking. Their propaganda machine ... caused cancer. At least two events advanced the belief that viruses caused cancer: one involved the Rous sarcoma virus ...
... cause of lung cancer.3,4 During World War II, the Nazis waged a campaign against smoking. Their propaganda machine ... caused cancer. At least two events advanced the belief that viruses caused cancer: one involved the Rous sarcoma virus ...
Página 6
... caused by carcinogens or viruses (for instance, liver cancer, which is rampant in parts of the Third World, is caused in large part by hepatitis B and C viruses), cancer is ultimately a disease of genes. Bruce Ames was a professor of ...
... caused by carcinogens or viruses (for instance, liver cancer, which is rampant in parts of the Third World, is caused in large part by hepatitis B and C viruses), cancer is ultimately a disease of genes. Bruce Ames was a professor of ...
Página 7
... causes normal cells to form tumors. There are about 50 oncogenes known thus far. In 1997, Weinberg's group cloned the first of ... cause cancer, a young scientist in Canada almost scooped him. In the late 1970s, Demetrios Spomdidos was a ...
... causes normal cells to form tumors. There are about 50 oncogenes known thus far. In 1997, Weinberg's group cloned the first of ... cause cancer, a young scientist in Canada almost scooped him. In the late 1970s, Demetrios Spomdidos was a ...
Contenido
3 | |
2 Drugs to Kill Germs | 43 |
From Nitroglycerin to Lipitor | 75 |
4 Sex and Drugs | 103 |
5 Drugs of the Mind | 129 |
6 Diabetes Drugs | 165 |
7 Anesthetics | 187 |
8 AntiInflammatory Drugs | 213 |
9 Reflections | 241 |
Chemical Structures | 245 |
Trademarks of the Drugs | 277 |
Bibliography | 281 |
Index | 295 |
Otras ediciones - Ver todas
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Términos y frases comunes
ACE inhibitors acid active agents alcohol anesthesia anesthetic antibacterial antibiotics antidepressants aphrodisiac approved aspirin Avastin Banting barbiturates became beta-blockers biological blood breast cancer Bristol-Myers Squibb calcium cancer drugs cause cells Chain chemical chemist chemistry chemotherapy chloroform chlorpromazine cholesterol clinical trials cocaine compounds cortisone depression developed diabetes discovered disease doses drug discovery EGFR enzyme estrogen ether extract Florey Gleevec guinea pigs haloperidol heart hormone human inhibit inhibitors initially injection insulin Iressa isolated kinase laboratory later leukemia leukotriene Lilly Lipitor lithium liver Macleod Marsilid medicine Merck metabolism mevastatin million molecule Morton nitroglycerin nitrous oxide Nobel Prize Novartis oral pancreas Parke-Davis patients penicillin Pfizer pharmaceutical Physiology production Prontosil prostaglandin protease protein Prozac receptor rheumatoid arthritis Roche scientists serotonin side effects Squibb statins streptomycin sulfanilamide Syntex synthesis tamoxifen Taxol tested therapy tion toxic trade name treating treatment tuberculosis tumors University Viagra virus Waksman