Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We UseOxford University Press, 2006 M09 7 - 336 páginas The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful. |
Dentro del libro
Resultados 1-5 de 42
Página ix
... therapeutic agent. Most people who have engaged in this effort for a lifetime have not been so fortunate. It is not easy to select a research objective that will turn out to be a winner. The enormous complexity of the human body ...
... therapeutic agent. Most people who have engaged in this effort for a lifetime have not been so fortunate. It is not easy to select a research objective that will turn out to be a winner. The enormous complexity of the human body ...
Página 11
... therapies and extensive surgical exploration, both pioneered at the Indiana University Medical Center by Lawrence Einhorn (oncologist) and John Donahue (surgical urologist), testicular cancer was generally fatal. When cyclist Lance ...
... therapies and extensive surgical exploration, both pioneered at the Indiana University Medical Center by Lawrence Einhorn (oncologist) and John Donahue (surgical urologist), testicular cancer was generally fatal. When cyclist Lance ...
Página 23
... therapy and included coverage of the control of hormonedependent tumors in the patent of tamoxifen, which primarily focused on the management of the sexual cycle. Walpole's inclusion of cancer as an indication in his application proved ...
... therapy and included coverage of the control of hormonedependent tumors in the patent of tamoxifen, which primarily focused on the management of the sexual cycle. Walpole's inclusion of cancer as an indication in his application proved ...
Página 24
... therapy (HRT) for postmenopausal discomforts was linked to an increase in breast cancer. Estrogen, the key trigger for two-thirds of all breast cancers, can fuel the growth of breast cancer cells. This is one of the reasons that ...
... therapy (HRT) for postmenopausal discomforts was linked to an increase in breast cancer. Estrogen, the key trigger for two-thirds of all breast cancers, can fuel the growth of breast cancer cells. This is one of the reasons that ...
Página 33
... therapeutic, but Genentech has this great policy that allows people to pursue their own interests.”36,37 As a consequence, Ferrara was able to follow what he really believed in. In 1993, he and colleagues developed a mouse antibody that ...
... therapeutic, but Genentech has this great policy that allows people to pursue their own interests.”36,37 As a consequence, Ferrara was able to follow what he really believed in. In 1993, he and colleagues developed a mouse antibody that ...
Contenido
3 | |
2 Drugs to Kill Germs | 43 |
From Nitroglycerin to Lipitor | 75 |
4 Sex and Drugs | 103 |
5 Drugs of the Mind | 129 |
6 Diabetes Drugs | 165 |
7 Anesthetics | 187 |
8 AntiInflammatory Drugs | 213 |
9 Reflections | 241 |
Chemical Structures | 245 |
Trademarks of the Drugs | 277 |
Bibliography | 281 |
Index | 295 |
Otras ediciones - Ver todas
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Laughing Gas, Viagra, and Lipitor: The Human Stories Behind the Drugs We Use Jie Jack Li Vista previa limitada - 2006 |
Términos y frases comunes
ACE inhibitors acid active agents alcohol anesthesia anesthetic antibacterial antibiotics antidepressants aphrodisiac approved aspirin Avastin Banting barbiturates became beta-blockers biological blood breast cancer Bristol-Myers Squibb calcium cancer drugs cause cells Chain chemical chemist chemistry chemotherapy chloroform chlorpromazine cholesterol clinical trials cocaine compounds cortisone depression developed diabetes discovered disease doses drug discovery EGFR enzyme estrogen ether extract Florey Gleevec guinea pigs haloperidol heart hormone human inhibit inhibitors initially injection insulin Iressa isolated kinase laboratory later leukemia leukotriene Lilly Lipitor lithium liver Macleod Marsilid medicine Merck metabolism mevastatin million molecule Morton nitroglycerin nitrous oxide Nobel Prize Novartis oral pancreas Parke-Davis patients penicillin Pfizer pharmaceutical Physiology production Prontosil prostaglandin protease protein Prozac receptor rheumatoid arthritis Roche scientists serotonin side effects Squibb statins streptomycin sulfanilamide Syntex synthesis tamoxifen Taxol tested therapy tion toxic trade name treating treatment tuberculosis tumors University Viagra virus Waksman