ASTRONOMICAL PHENOMENA.

Affect all bodies, 9.

Gravity, 9.

Binary stars, and the revolution of our

sun around a distant centre, illustra-
tions of the wide reign of the law of
gravity, 9-11.

Stability of the solar system, 12.

Order and harmony of the planetary sys-
tem, 12.

Relations of plants and animals to the
force of gravity, and the size of our
globe, 13.

Relations of the moon to the earth, with
its plants and animals, 14.
Heat of the sun and fixed stars, 16.
Researches of Pouillet upon heat of fixed
stars, 16.

Relations of the fixed stars to the motions
upon the earth, and to the existence of
plants and animals, 17-20.
Acalephæ, blood of, 80.
Andral, on the changes of the blood in
typhoid fever, 198; in smallpox, 199; in
measles, 199; in erysipelas, 200; in phthi-
sis, 200;
in acute rheumatism, 202; in
pleuritis, 203; in peritonitis, 203; in bron-
chitis, 203.

on the distinctions between the altera-
tions of the blood in the pyrexiæ and
phlegmasiæ, 208–210.

Anemia, changes of blood in, 201.
Antony, Dr. Milton, on spinal irritation,

152.

Arnold, Dr. Richard D., on the color of the
liver in malarial fever, 244.

BLOOD, 75-216.

Imperfect state of our knowledge, 75.
Importance and difficulty of establishing
a standard formula of the constitution
of the blood in health, 79.

The constitution of the blood varies not
only with the class, but with each spe-
cies of animals, and corresponds with
the development and perfection of the
organs and apparatus, 80.
Blood of Protozoa, 80.

Polypi, 80.
Acalephæ, 80.
Echinodermata, 81.
Cephalopoda, 82.

Amphioxus, 82.

Garfish (lepisosteous osseus),
83.

Reptiles, 83.

Birds and mammalia, 83.

Chemical constitution of moist blood cor-
puscles, 84.

Chemical constitution of liquor sanguinis,
84.

Importance of establishing the typical

formula of the blood in starvation, 85.
Difficulties of establishing the amount of
blood in health and disease, 86.
Estimates of the amount of blood in the
human system by Blumenbach, Haller,
Borelli, Young, Dumas, Fletcher, An-
cell, Valentine, and Lehmann, and by
the author, 86.

Changes of the blood in malarial fever,
88, 216.

Difficulties of investigations upon the blood
in disease, 88.

Color of the blood and serum in malarial
fever, 91.

Specific gravity of the blood and serum
in various diseases, as determined by
Becquerel, Rodier, Nasse, Zimmerman,
Guenaud de Mussy, and Joseph Jones,
93.
Coagulation of the blood, 93.

BLOOD-continued.

Table of blood-corpuscles in 1,000 parts
of healthy and malarial blood, 94.
Fibrin in healthy and diseased blood, as
determined by Andral, Gavarret, Bec-
querel, Rodier, Guenaud de Mussy,
Popp, Wittstock, Simon, Glover, Heller,
and Joseph Jones, 94, 95.

Cases illustrating the physical changes of
the fibrin, and the formation of heart
clots in malarial fever, 96-112.
Observations of Hewson, Baillie, Mor-
gagni, Albinus, Burns, Stewart, War-
drop, Cruwell, Graham, Stenzel, Meckel,
Stoerk, Petit, O'Halloran, Martial, Ba-
ron, Virchow, Paget, Crampton, Louis,
Bougen, Desault, Duncan, Reid, Hodg-
son, Andral, Tiedemann, Otto, Lobstein,
Cloquet, Carsewell, Langstaff, and Ri-
chardson, on the formation of fibrinous
concretions during life, 113-115.
Conditions most favorable to the deposi-
tion of fibrinous concretions, 115-117.
Observations of Gairdner, Richardson,
Gaspard, Lee, Hewson, Thackrah, Coo-
per, and Brücke, upon the coagulation
of the blood, 116, 117.

Symptoms and diagnosis of fibrinous con
cretions in the heart and blood vessels,
118-124.

Observations of Dr. Wm. Senhouse Kirkes
upon the effects of detachment of fibrin-
ous concretions during life, 125.
Discussion of the causes of the formation
of fibrinous concretions in the heart
and blood vessels in malarial fever, 126
-129.

Principles of treatment best adapted to

prevent the formation of fibrinous con-
cretions in the heart and blood vessels,
129-132.

Method of analyzing the blood, 133.
Table illustrating the composition of ven-
ous blood in malarial fever, 135.
History of the cases which furnished the
blood for analyses, 136-171.
Comparison of their results with the typi-
cal formula of the blood in health and
disease, 171-211.

Colored blood-corpuscles are diminished
during malarial fevers, and the extent
and rapidity of the diminution corre-
spond to the severity and extent of the
disease, 171.

Researches of Andral and Gavarret upon
the blood of intermittent fever, 172.
Composition of the blood in marsh cach-

exia, according to Becquerel & Rodier,
173.

Composition of the blood in mechanical
dropsy, 174.

Composition of the blood in acute dropsy,
175.

Composition of the blood in cachectic drop-
sies, 177.

The fixed saline constituents of the col-
ored blood-corpuscles are diminished in
malarial fever, 177.

The iron of the disintegrated blood-corpus-
cles appears in the urine, 178.

BLOOD-continued.

Physiological, pathological, and thera-
peutical bearing of the changes of the
blood-corpuscles in malarial fevers, 178

-193.
Researches of Schmidt upon the specific
gravity of the colored blood-corpuscles
in various diseases, 179.
Relations of the colored blood-corpuscles
to the muscular and nervous system,
179.

Principles of treatment, based upon the
changes of the blood in malarial fever,
180-193.

Injurious effects of bloodletting in mala-
rial fever, 180-186.

Active and excessive purgation should be
avoided in malarial fever, 187.
Importance of nutritious diet, and of the
phosphates and iron, 188.

Principles which should govern the admin-
istration of pepsin in malarial fever,
189.

The excretion of the products resulting
from the dead disintegrated blood-cor-
puscles should be promoted by diuretics
and depurants, and the liver and spleen
should be roused to throw off their per-
verted secretions, 193.

Place of the destruction of the colored
corpuscles in malarial fever, 194.
Animal starch accumulates in the malarial
liver; whilst grape sugar is absent,

195.

Alterations of the blood, and especially of
the blood-corpuscles in the spleen during
malarial fever, 196.

Comparison of the changes of the blood
in malarial fever, with the changes of
the blood in typhoid fever, typhus fever,
ephemeral fever, smallpox, scarlatina,
measles, acute scurvy, chronic scurvy,
erysipelas, cholera, phthisis, scrofula,
carcinoma, Bright's disease, chlorosis,
anemia, simple rheumatic fever, febrile
arthritic rheumatism, rheumatism, puer-
peral fever, pneumonia, pleuritis, peri-
tonitis, angina tonsillaris, acute bron-
chitis, carditis, pericarditis, inflamma-
tion of brain, glanders, and lead poi-
soning, 198-203.

The colored blood-corpuscles are more uni-
formly and rapidly destroyed in mala-
rial fever than in any other acute dis-
ease, 204-207.

Comparison of the changes of the blood
and organs in malarial fever, with the
changes of the blood and organs in ty-
phoid and typhus fevers, 205-207.
The diminution of fibrin in malarial fever
corresponds with the severity of the
disease, 208

Observations of Andral upon the diminution
of fibrin in fevers, 208-210.
Discussion of the question, do these
changes of the blood precede or suc-
ceed, or are they simultaneous with, the
aberration of the physical, chemical,
vital, and nervous phenomena denomi-
nated fever, 211–216.

CEREBRO-SPINAL NERVOUS SYSTEM, 217-
231.

Not the seat in malarial fever of any uni-
form irritation or inflammation, 219.
Discussion of the causes of the aberrated

nervous phenomena of malarial fever,
220.

Theory expressing the relations of the

physical, chemical, and nervous pheno-
mena of malarial fever, 221.
Malarial fever paroxysmal not because the
action of the cerebro-spinal or of the
sympathetic nervous system is parox-
ysmal, 223.

Explanation of the paroxysmal character
of malarial fever, 221-223.
Post-mortem examinations of the cerebro-
spinal nervous system in the various
forms of malarial fever, 224-231.

CHEMICAL CHANGES.

Importance of determining the amounts
and character in various disease, 271-
276.

Index of temperature, 271-276.
Chemical changes of blood, 88-216.

liver, 195, 240.
spleen, 196, 259.
intermittent fever,
285.
remittent fever, 312.
congestive fever, 352.

Relations of, to respiration, temperature,
state of skin, and changes of urine in
intermittent, remittent, and congestive
fever, 271-407.

Importance of its determination, 275.
Table showing the variations of in differ-
ent individuals, 277.

Effects of changes of temperature on, 282.
Condition of, in the cold stage of intermit-
tent fever, 285-293.

In the hot stage, and period of intermis-
sion, 293-312.

Cases and tables illustrating the changes of

the circulation in intermittent, remit-
tent, and congestive fevers, 301-407.

CORRELATION OF THE PHYSICAL AND VITAL
FORCES, 24-48.

History of the establishment of the cor-

relation of the physical forces, 26-36.
Views of the Hindoos, Sabians, Chinese,
Persians, and Egyptians, of Thales,
Parmenides, Archelaus, Democritus,
Pythagoras, Hippocrates, and other an-
cient philosophers, 26.

Labors, experiments, reasonings, and
generalizations in astronomy, of Ar-
chimedes, Anaximander, Aristotle, An-
aximenes, Aristarchus, Hipparchus, Pto-
lemy, Copernicus, Kepler, Stevinus,
Galileo, Gassendi, Fermat, Riccioli,
Grimaldi, Bacon, Descartes, Castelli,
Huyghens, Hooke, Halley, Mersenne,
Bernoulli, Hermann, Leibnitz, Euler,
Clairaut, D'Alembert, Lagrange, Gas-
sendi, Borelli, and Newton, 27, 28;
in acoustics, of Pythagoras, Mersenne,
Newton, Taylor, Bernoulli, D'Alembert,
Euler, Lagrange, Laplace, Poisson, 28;
in thermotics, of Bacon, Locke, Rum-
ford, Davy, Leslie, Dulong, Clausius,
Mayer, Magnus, Holtzmann, Regnault,
Rankine, Thompson, Joule, 29; in
optics, of Seneca, Ptolemy, Archimedes,
Euclid, Alhazen, Vitello, Snell, Greg-
ory, Descartes, De Dominis, Newton,
Huyghens, Grimaldi, Biot, Arago,
Hooke, Young, Fresnel, Brewster, 30;
of Volta, Nicholson, Davy, Becquerel,
Faraday, Oersted, Arago, Schweigger,
31-32; of Petit, Scheele, Senebier,
Rumford, Meese, Priestley, Ingenhousz,
Saussure, Ritter, Wollaston, Young,
Vogel, Herschel, Seebeck, Gay-Lussac,