The Reader's Digest, Volumen171Reader's Digest Association, 2007 |
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... [ MRHD ] based on an area under the concentration - time curve ( AUC ) comparison ) . The no - effect level for hepatic tumors in female mice was 100 mg / kg / day ( 827 - times and 12 - times the therapeutic exposure to ramelteon and M ...
... [ MRHD ] based on an area under the concentration - time curve ( AUC ) comparison ) . The no - effect level for hepatic tumors in female mice was 100 mg / kg / day ( 827 - times and 12 - times the therapeutic exposure to ramelteon and M ...
Página 25
... MRHD on a mg / m2 basis ) and 600 mg / kg / day in males ( 786 - times higher than the MRHD on a mg / m2 basis ) when considering all studies . Pregnancy : Pregnancy Category C Ramelteon has been shown to be a developmental teratogen in ...
... MRHD on a mg / m2 basis ) and 600 mg / kg / day in males ( 786 - times higher than the MRHD on a mg / m2 basis ) when considering all studies . Pregnancy : Pregnancy Category C Ramelteon has been shown to be a developmental teratogen in ...
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