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of the methods of preparing pure cultures for purposes of diagnosis. As regards the etiology of cholera, the ground taken by the editor is that, while Koch’s doctrine has not been finally established as a scientific truth, it has very much in its favor. At the same time space has been given to opinions directly traversing the points claimed by the German investigator. It will be seen, therefore, that the editor has treated the subject in an unbiased way. And indeed the extremely divergent opinions regarding cholera entertained even at the present day would scarcely justify an attempt to present a completely harmonious picture of the disease.

The editor has relied for information upon those American, English, French, German, Italian and Spanish writers who are recognized in their own countries as the highest authorities upon the subject.

For valuable assistance in summarizing foreign writings he would here express his obligations to Dr. T. L. Stealman, of this city. His thanks are also due to Dr. J. C. Peters and Dr. A. Jacobi, for placing at his disposal their valuable libraries. Finally, the indulgence of the reader is asked for any typographical errors that, in the somewhat hasty proof-reading, may have been overlooked.


New York, May, 1885.

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