2. Each essay shall be marked with some distinguishing device or motto, and accompanied by a sealed envelope bearing the same device or motto, and containing the name and address of the writer.

3. The essay selected by the committee shall be transmitted by them. together with its accompanying envelope, to the council of the New York Academy of Medicine, under whose direction the envelope shall be opened and the name of the writer announced at the first meeting of the Academy in May, 1869.

4. This prize is open for universal competition.

5. The committee have a right to reject whatever does not come up to a proper standard of merit. ALFRED C. POST, M.D.,

President of the Academy, on behalf of the Council. COMMITTEE OF AWARDS.-J. C. DALTON, M.D., Professor of Physiology in the College of Physicians and Surgeons, New York; A. FLINT, JR., M.D., Professor of Physiology in the Bellevue Hospital Medical College, New York; ALFRED L. LOOMIS, M.D', Professor of the Institutes and Practice of Medicine in the University Medical College, New York.

The unavoidable delay in the publication of this number of our Journal owing to the destruction of the printing establishment in the late conflagration on Main street, has been longer than we could anticipate, and our readers can not deprecate this more than we do ourselves. It will not affect the next number, however, due July 10th.

We have been obliged to postpone some valuable communications for publication until our next issue.

BOOKS AND PAMPHLETS Received.

MORGAN, Electro-Physiology and Therapeutics. Wood & Co. 1868. Svo.

New York: Wm.

CULLERIER, Atlas of Venereal Diseases. Translated, with notes and additions by Bumstead. With about 150 colored figures on 26 plates. Parts I-III. Philad. Henry C. Lea. RICORD, Chart of Venereal Diseases.

1868.

Moos, Klinik der Ohrenkrankheiten.

Svo.

1868. Imp. 4to.

New York: Wm. Wood & Co.

Wien: W. Braumüller. 1866.

With notes

HOLDEN, Manual of the Dissection of the Human Body.

and additions by Erskine Mason, M.D. New York: R. M. DeWitt, (1868). Svo.

DESORMEAUX, The Endoscope.

Transl. by R. P. Hunt, M.D. (Reprinted from the Chicago Medical Journal). Chicago: 1868. 8vo.

Medical Report upon the Uniform and Clothing of Soldiers of the U. S. Army. Surgeon General's Office. 1868. Svo. Pamphlet.

STILLÉ, Therapeutics and Materia Medica. A systematic treatise, etc., etc. 3d edition, revised and enlarged. Philad. Henry C. Lea. 2 vols. Svo.

Orthopedic Apparatus and Description of the Mechanical Appliances employed in the treatment of Deformities, etc., with directions for taking measurements. By D. W. Kolbé, Manufacturer, etc. Philad.: 1868.

Svo. pamphlet.

Fox, TILBURY, On Impetigo Contagiosa. (Rep. from Brit. Med. Journal). London: 1864. 16mo. pamphlet.-From the author.

(Rep.

The nature of so-called Parasites" of the Skin. from Brit. Med. Journal). London: 1864. 16mo. pamphlet.-From the author.

BIDDLE, Materia Medica. For the use of students. Philad. Lindsay & Blakiston. 1868. Svo.

:

3d edition.

WILSON, ERASMUS, On Diseases of the Skin. With 20 plates. 7th American, from the 6th and enlarged English edition. Philad.: Henry C. Lea. 1868. 8vo..

CHAMBERS, The Indigestions; or Diseases of the Digestive Organs functionally treated. 2d American, from the 2d and revised London edition. Philad.: H. C. Lea. 1868. Svo.

Constitution, By-Laws, etc. of the San Francisco Medical Society. San Franc. 1868. Svo. pamphlet.

DAMON. The Neuroses of the Skin: their pathology and treatment. Philad. Lippincott & Co. 1868. Svo.

Report on Epidemic Cholera and Yellow Fever in the Army of the United States, during the year 1867. By Bvt. Lieut.-Col. J. J. WoodWARD, Assist. Surgeon U. S. A. Surgeon General's Office, Circular No. 1. Washington, 1868. 4to.-From Surgeon General's Office.

LOOMIS, Lessons in Physical Diagnosis. New York: Robt. M. DeWitt. 1868. Svo.

†The ratio of deaths per annum per mille of inhabitants. The number of inhabitants not being exactly known and constantly varying, these figures are approximative only, based on the official estimates of the population.

THE SAINT LOUIS

Medical and Surgical Journal.

JULY 10, 1868.

Original Communications.

CLINICAL LECTURE ON CHANCRE.

Delivered at the St. Louis (Sisters') Hospital, by E. H. GREGORY, M.D., Adjunct Professor of Surgery in the St. Louis Medical College.

GENTLEMEN :—

[Reported by W. B. OUTTEN, M.D.]

It has been my constant care to occupy your precious time in the most profitable manner possible, hence I pass by all matters of controversy relating to the important subject of to-day's lecture, and direct attention at once to points essentially practical.

You have frequent opportunities in this clinic of studying syphilis from original sources. Good examples of chancroid and chancre are not uncommon, and your minds are doubtless indelibly impressed with many of the distinctive features pertaining respectively to these two varieties of venereal disease.

Chan

Mark well the declaration which I now make. croid is, under all circumstances, a local disease. On the contrary, syphilis, represented by chancre as its initial lesion, is, under all circumstances, a constitutional disease. Chancroid is the direct result of a specific virus which

means.

implicates only contiguous parts, and is curable by local On the contrary, chancre, like the vaccine sore, is the indirect result of a specific virus. I say indirect, because both these affections are the direct consequence of systemic conditions, superinduced by their respective poisons. Syphilis and vaccina are not known as local diseases simply. From the moment of contact, the work of constitutional contamination is in progress, and as the mature vaccine pustule announces the completion of the period of incubation in the disease to which it pertains, so the perfected chancre proclaims the accomplishment of constitutional syphilis. Here the analogy between syphilis and vaccina ceases, for a second period of incubation succeeds to chancre which is peculiar to syphilis, and issues in the eruption of the so-called secondary disease. The peculiarity of second incubation probably accounts for the disassociation of syphilis from the class of diseases to which it belongs, as also for the current error that chancre contaminated the constitution, rather than itself resulted from systemic infection.

I again repeat, the importance of a correct diagnosis of venereal sores must be apparent to you all, as by far the larger proportion of these cases require local treatment alone, the general employment of iodine and mercury proving decidedly injurious.

With the aid of your attention I will attempt to describe the local venereal sore.

Ist, Chancroids appear within a few hours, at most within a few days after infection. 2d, chancroids are more frequently multiple than single; when but one appears at the outset, others are apt to spring up from successive inoculation. 3d, chancroids are pustules before they are ulcers. 4th, chancroids show much inflammation and furnish pus freely. 5th, chancroids are soft, no induration, edges loose. 6th, chancroids have abruptly-cut edges, through the entire thickness of skin or mucous membrane. 7th, chancroids are auto-inoculable and rarely implicate neighboring