The Reader's Digest, Volumen158DeWitt Wallace, Lila Acheson Wallace Reader's Digest Association, 2001 |
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Página 185
... human exposure as measured by the AUC0-24 at 200 mg BID ) or in mice given oral doses up to 25 mg / kg for males and 50 mg / kg for females ( approximately equal to human exposure as measured by the AUC0-24 at 200 mg BID ) for two years ...
... human exposure as measured by the AUC0-24 at 200 mg BID ) or in mice given oral doses up to 25 mg / kg for males and 50 mg / kg for females ( approximately equal to human exposure as measured by the AUC0-24 at 200 mg BID ) for two years ...
Página 57
... human dose ( HD ) on a mg / kg body weight basis , serum drug levels were only 6 to 10 times higher than those measured in humans given 40 mg pravastatin as meas- ured by AUC . In a 2 - year study in mice fed pravastatin at doses of 250 ...
... human dose ( HD ) on a mg / kg body weight basis , serum drug levels were only 6 to 10 times higher than those measured in humans given 40 mg pravastatin as meas- ured by AUC . In a 2 - year study in mice fed pravastatin at doses of 250 ...
Página 69
... human exposure as measured by the AUC0-24 at 200 mg BID ) or in mice given oral doses up to 25 mg / kg for males and 50 mg / kg for females ( approximately equal to human exposure as measured by the AUC0-24 at 200 mg BID ) for two years ...
... human exposure as measured by the AUC0-24 at 200 mg BID ) or in mice given oral doses up to 25 mg / kg for males and 50 mg / kg for females ( approximately equal to human exposure as measured by the AUC0-24 at 200 mg BID ) for two years ...
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