The Reader's Digest, Volumen162Reader's Digest Association, 2003 |
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Página 20
... rats , dose - related embryofetal toocty and postnatal developmental toxicity 20 - MG , 40 - MG Delayed - Release Capsules 138.0 mg / kg / day ( about 5.6 to 56 times the human doses on a body surface area basis ) . 300,000 cards each ...
... rats , dose - related embryofetal toocty and postnatal developmental toxicity 20 - MG , 40 - MG Delayed - Release Capsules 138.0 mg / kg / day ( about 5.6 to 56 times the human doses on a body surface area basis ) . 300,000 cards each ...
Página 132
... rats . Female rats were not affected . Although there was a dose - related increase in the number of tumors in mice , there was no drug - related increase in the number of mice with tumors . The clinical significance of these findings ...
... rats . Female rats were not affected . Although there was a dose - related increase in the number of tumors in mice , there was no drug - related increase in the number of mice with tumors . The clinical significance of these findings ...
Página 24
... rats , loratadine was administered in the diet at doses up to 40 mg / kg / day in mice ( estimated desloratadine and desloratadine metabolite exposures were approximately 3 times the AUC in humans at the recommended daily oral dose ) ...
... rats , loratadine was administered in the diet at doses up to 40 mg / kg / day in mice ( estimated desloratadine and desloratadine metabolite exposures were approximately 3 times the AUC in humans at the recommended daily oral dose ) ...
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